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Mental Health Grants in Indiana 2026 — Federal Funding Opportunities

Federal funding for mental health research, treatment programs, and behavioral health services from SAMHSA, NIMH, and HHS. GrantMetric surfaces every active federal notice of funding opportunity (NOFO) relevant to Indiana applicants, with award ceiling, eligibility requirements, and close dates visible at a glance.

  • 83 active federal grants open to Indiana organizations
  • Eligible applicants: nonprofits, universities, state agencies, small businesses
  • Award floor and ceiling for each funding opportunity
  • Application deadlines and close dates from grants.gov — updated daily
  • AI-generated briefings summarizing each program's objectives
Active Grants: 83 // State: Indiana // Source: Grants.gov // Updated: Daily
Federal Grants in Indiana

Federal grants are available nationally — Indiana organizations apply directly to federal agencies. These 83 active opportunities are open to eligible applicants in Indiana right now.

Indiana — Mental Health Grants Intelligence

83 active mental health grants currently open to Indiana applicants on Grants.gov. Funding agencies: HHS-NIH11, DOE-ID, HHS-CDC-OPHPR, HHS-OPHS, USDOJ-OJP-COPS, HHS-SAMHS-SAMHSA. Largest award ceiling: $59.0M. 27 grants closing within 30 days.

Federal grants are open nationally — Indiana nonprofits, state agencies, universities, small businesses, and local governments apply directly to the funding agency. Eligibility requirements, award floors and ceilings, and application deadlines are listed on each opportunity's detail page. All data is sourced from Grants.gov and updated daily. Use the grant cards below to review open solicitations and click through to the full Notice of Funding Opportunity (NOFO) before applying.

Active Opportunities for Indiana (83)

PAR-25-286 01/07/2028
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications seeking to develop the next genera...

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PAR-25-101 08/11/2027
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
Agency HHS-NIH11

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innov...

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PAR-25-347 09/07/2026
Substance Use/Substance Use Disorder Dissertation Research Award (R36 Clinical Trials Not Allowed)
Agency HHS-NIH11

The goal of this NOFO is to support doctoral candidates from a variety of academic disciplines for up to two years for t...

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DE-FOA-0002265 10/14/2030
University Nuclear Leadership Program– Scholarship and Fellowship Support
Agency DOE-ID

A. STATEMENT OF OBJECTIVES This Funding Opportunity Announcement (FOA) is to award multiple cooperative agreements to ac...

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PAR-26-001 05/07/2027
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)
Agency HHS-NIH11

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Of...

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PAR-25-066 09/07/2026
Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional)
Agency HHS-NIH11

This initiative seeks to solicit applications for research projects that address the link between social disconnection i...

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PAR-25-136 01/07/2028
Laboratories to Optimize Digital Health (R01 Clinical Trial Required)
Agency HHS-NIH11

NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effective...

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PAR-25-204 11/12/2027
NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The ove...

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PAR-25-281 01/07/2028
Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the e...

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PAR-25-285 10/15/2027
Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)
Agency HHS-NIH11

This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure develo...

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PAR-25-177 10/15/2027
Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)
Agency HHS-NIH11

Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01 Clinical Trial Requi...

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PAR-25-207 01/07/2028
Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Agency HHS-NIH11

NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interven...

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PAR-25-291 01/07/2028
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
Agency HHS-NIH11

Reissue of RFA-20-351.The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications to pursue in...

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PAR-25-288 01/07/2028
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family naviga...

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PAR-25-282 01/07/2028
Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the e...

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PAR-24-297 01/07/2028
Imaging - Science Track Award for Research Transition (I/START) (R03 Clinical Trial Optional)
Agency HHS-NIH11

This Notice of Funding Opportunity Announcement (NOFO) is designed to encourage and facilitate the entry of investigator...

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PAR-25-289 01/07/2028
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family naviga...

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PAR-25-310 01/07/2027
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)
Agency HHS-NIH11

This NOFO is a call to action in response to the mental health crisis in the United States. We seek applications that wi...

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PAR-24-269 02/11/2027
NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants tha...

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PAR-25-178 10/15/2027
Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)
Agency HHS-NIH11

Pilot Effectiveness Trials for Treatment, Preventive and Services Interventions (R01 Clinical Trial Required). As part o...

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PAR-25-040 09/07/2026
Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)
Agency HHS-NIH11

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagn...

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PAR-25-065 09/07/2026
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)
Agency HHS-NIH11

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowl...

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PAR-25-154 07/16/2026
HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to identify new d...

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CDC-RFA-TP22-2201 02/11/2027
Public Health Crisis Response Cooperative Agreement
Agency HHS-CDC-OPHPR

CDC seeks to enhance the nation’s ability to rapidly mobilize, surge, and respond to public health emergencies (PHEs) ...

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PAR-25-353 10/25/2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
Agency HHS-NIH11

Reissue of PAR-20-119. This FOA encourages applications to advance the discovery, preclinical development, and proof of ...

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PAR-25-352 10/25/2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
Agency HHS-NIH11

Reissue of PAR-20-118. This Notice of Funding Opportunity (NOFO) encourages applications to advance the discovery, precl...

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PAR-25-283 01/07/2028
Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Announcement (NOFO) is to encourage innovative research that will inform and suppo...

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PAR-25-284 01/07/2028
Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Announcement (NOFO) is to encourage pilot research that is not an immediate precur...

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PAR-25-290 01/07/2028
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications to pursue invasive neural recordin...

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RFA-DA-26-034 11/18/2027
Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

This notice of funding opportunity (NOFO) will support research towards understanding and mitigating the deleterious eff...

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RFA-ES-25-002 04/20/2027
Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)
Agency HHS-NIH11

This Notice of Funding Opportunity Announcement (NOFO) invites grant applications for Environmental Health Sciences Core...

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PAR-25-446 08/21/2028
Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and...

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PAR-24-027 10/30/2026
Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)
Agency HHS-NIH11

The Population Assessment of Tobacco and Health (PATH) Study provides the scientific community with biospecimens (urine,...

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PAR-24-089 11/13/2026
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)
Agency HHS-NIH11

This funding opportunity announcement (FOA) encourages applications for institutional research career development (K12) ...

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PAS-25-236 09/07/2027
D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional)
Agency HHS-NIH11

Data science is an important cross-cutting research approach in the 2022 - 2026 NIDA Strategic Plan and increasing the c...

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PAR-25-064 09/07/2026
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)
Agency HHS-NIH11

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowl...

Health View Details →
PAR-25-287 01/07/2028
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications seeking to develop the next genera...

Health View Details →
PAR-25-206 01/07/2028
Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Agency HHS-NIH11

NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and se...

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PAR-25-226 11/19/2026
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications that bundle independent protocols for...

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PAR-25-180 10/15/2027
First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage cooperative agreement applications to support e...

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PAR-25-039 09/07/2026
Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)
Agency HHS-NIH11

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagn...

Health View Details →
PAR-25-067 09/07/2026
Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)
Agency HHS-NIH11

This initiative seeks to solicit applications for research projects that address the link between social disconnection i...

Health View Details →
RFA-DA-26-055 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Opportunity Announcement (NOFO) is to invite applications proposing the innovative analysi...

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RFA-DA-26-056 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this notice of funding opportunity (NOFO) is to invite applications proposing the innovative analysis of ...

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RFA-DA-25-060 03/05/2027
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of H...

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RFA-DA-25-024 03/06/2027
High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of H...

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RFA-DA-27-016 02/09/2029
HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)
Agency HHS-NIH11

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PAR-27-081 03/05/2027
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capabilit...

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PA-FPH-27-001 01/09/2027
Title X Family Planning Services Grants
Agency HHS-OPHS

The Office of Population Affairs (OPA) announces the anticipated availability of funds for Fiscal Year (FY) 2027 grants ...

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PAR-27-026 09/25/2028
Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional)
Agency HHS-NIH11

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O-COPS-2026-172553 07/30/2026
FY26 Law Enforcement Mental Health and Wellness Act Program
Agency USDOJ-OJP-COPS

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SP-26-004 07/13/2026
Tribal Behavioral Health Substance Use Prevention
Agency HHS-SAMHS-SAMHSA

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RFA-ES-27-004 09/25/2028
Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)
Agency HHS-NIH11

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardou...

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RFA-DA-27-015 09/30/2026
Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this notice of funding opportunity (NOFO) is to establish a Center that trains researchers in formal prod...

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26PR05 07/31/2026
Advancing Behavioral Health in Corrections: Training and Policy Innovation Initiative
Agency USDOJ-BOP-NIC

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SM-26-029 07/15/2026
Behavioral Health Mobile Crisis Team Partnerships
Agency HHS-SAMHS-SAMHSA

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SM-26-025 07/15/2026
Behavioral Health Partnerships for Early Diversion of Adults and Youth
Agency HHS-SAMHS-SAMHSA

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SM-26-024 07/16/2026
Tribal Behavioral Health: Suicide Prevention
Agency HHS-SAMHS-SAMHSA

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TI-26-012 07/16/2026
Tribal Opioid Response
Agency HHS-SAMHS-SAMHSA

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TI-26-021 07/16/2026
Rural Opioid Technical Assistance Centers
Agency HHS-SAMHS-SAMHSA

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TI-26-015 07/16/2026
Grants to Expand Substance Use Disorder Treatment Capacity in Adult and Family Treatment Drug Courts
Agency HHS-SAMHS-SAMHSA

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SM-26-015 08/17/2026
Certified Community Behavioral Health Clinic (CCBHC) Improvement and Advancement Grant
Agency HHS-SAMHS-SAMHSA

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SM-26-007 07/06/2026
Adult Suicide Prevention
Agency HHS-SAMHS-SAMHSA

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SM-26-020 07/16/2026
Infant and Early Childhood Mental Health
Agency HHS-SAMHS-SAMHSA

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FG-26-004 07/17/2026
988 Suicide and Crisis Lifeline Crisis Center Follow-Up Programs
Agency HHS-SAMHS-SAMHSA

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SM-26-016 08/17/2026
Cooperative Agreements for Certified Community Behavioral Health Clinic (CCBHC) Planning Grants
Agency HHS-SAMHS-SAMHSA

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SM-26-014 08/17/2026
Certified Community Behavioral Health Clinics (CCBHCs) Planning, Development, and Implementation Grant
Agency HHS-SAMHS-SAMHSA

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HRSA-26-102 07/17/2026
Screening & Treatment for Maternal Mental Health and Substance Use Disorders (MMHSUD)
Agency HHS-HRSA

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HRSA-26-058 07/10/2026
Pediatric Mental Health Care Access Program (PMHCA)
Agency HHS-HRSA

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HRSA-26-037 07/08/2026
Rural Communities Opioid Response Program (RCORP)-Impact
Agency HHS-HRSA

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HRSA-26-036 07/08/2026
Rural Communities Opioid Response Program (RCORP)-Planning
Agency HHS-HRSA

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HT942526TBIPHRPCTA 10/15/2026
DoW Traumatic Brain Injury and Psychological Health, Clinical Trial Award
Agency DOD-AMRAA

Summary: The fiscal year 2026 (FY26) Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) Clinical...

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RFA-DA-27-007 10/01/2026
Limited Competition: Growing Great Ideas: Research Education Course in Entrepreneurship and Product Development for Researchers Studying Drug Use, Drug Misuse, and Drug Addiction (UE5 Clinical Trial Not Allowed)
Agency HHS-NIH11

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HRSA-26-038 07/27/2026
Rural Communities Opioid Response Program (RCORP)-Technical Assistance
Agency HHS-HRSA

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SM-26-023 07/13/2026
Behavioral Health and Community Safety Partnerships
Agency HHS-SAMHS

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TI-26-008 07/27/2026
Medication-Assisted Treatment - Prescription Drug and Opioid Addiction
Agency HHS-SAMHS-SAMHSA

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SM-26-009 07/27/2026
GLS Campus Suicide Prevention Grant Program
Agency HHS-SAMHS-SAMHSA

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TI-26-006 07/27/2026
First Responders-Comprehensive Addiction and Recovery Act
Agency HHS-SAMHS-SAMHSA

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SM-26-021 07/27/2026
Promoting the Integration of Primary and Behavioral Health Care: States
Agency HHS-SAMHS-SAMHSA

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TI-26-020 07/27/2026
Center of Excellence for Protected Health Information Related to Behavioral Health
Agency HHS-SAMHS-SAMHSA

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SM-26-030 07/27/2026
Mental Health Awareness Training Grants
Agency HHS-SAMHS-SAMHSA

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TI-26-018 07/27/2026
Emergency Department Alternatives to Opioids Program
Agency HHS-SAMHS-SAMHSA

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O-BJA-2025-172612 07/14/2026
BJA FY25 State Criminal Alien Assistance Program (SCAAP)
Agency USDOJ-OJP-BJA

This NOFO seeks applications for payments under the statutorily required State Criminal Alien Assistance Program (SCAAP)...

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Frequently Asked Questions

What mental health grants are available in Indiana?
SAMHSA distributes Community Mental Health Services Block Grants to states, which Indiana allocates to local providers. Federally Qualified Health Centers (FQHCs), community mental health centers, and nonprofits in Indiana can also apply directly to SAMHSA competitive grants.
Can Indiana crisis centers get federal funding?
Yes. SAMHSA provides funding to states to staff and operate the 988 Suicide & Crisis Lifeline. Crisis centers, behavioral health organizations, and state agencies in Indiana can apply for operational funding through SAMHSA's crisis services portfolio.
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